“Reverse-Uptake” of Zinc-specific Fluorophore in the Prostate by Trans-rectal Florescence Diffuse Optical Tomography

نویسندگان

  • Guan Xu
  • Daqing Piao
  • Chris J. Frederickson
  • Hamid Dehghani
چکیده

Using fluorophore specific to zinc, a well-established prostate cancer marker, to detect prostate cancer will be challenged by the “reverse-uptake” of the fluorophore. A sensitivityadapted reconstruction method may improve the target recovery in axial-imaging geometry. ©2010 Optical Society of America OCIS codes: (170.7230) Urology; (170.6960) Tomography; (170.3010) Image reconstruction techniques; (170.7230) Spectroscopy, fluorescence and luminescence

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Sagittal-imaging Trans-rectal Optical Tomography Reconstruction with Structural Guidance: Initial Simulative Study

The reconstruction of sagittal trans-rectal optical tomography for prostate imaging is presented with assumption of structural guidance from trans-rectal ultrasound. The spatial prior combined with Jacobian weighing improves the recovery of lesion depth. © 2008 Optical Society of America OCIS codes: (170.6960) Tomography; (170.3010) Image reconstruction techniques; (170.7230) Urology

متن کامل

Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate, part I: simulation.

We investigate the feasibility of trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator that is to be integrated with a trans-rectal ultrasound (TRUS) probe. Integration with TRUS ensures accurate endo-rectal positioning of the NIR applicator and the utility of using TRUS spatial prior information to guide NIR image reconstruction. The prostate NIR ...

متن کامل

Phase IIa Clinical Trial of Trans-1-Amino-3-18F-Fluoro- Cyclobutane Carboxylic Acid in Metastatic Prostate Cancer

Objective(s): We performed a phase IIa clinical trial of trans-1-amino-3-18Ffluoro-cyclobutane carboxylic acid (anti-18F-FACBC), a synthetic amino acid analog for PET, in patients with metastatic prostate cancer. Methods: The study subjects consisted of 10 untreated prostate cancer patients having lymph node and/or bone metastasis. Five patients underwent whole-body PET 5 and 30 min after intra...

متن کامل

بررسی ارزش Diffusion Weighted Imaging در تصاویر MRI برای تشخیص سرطان پروستات

Background: Prostate cancer is the third leading cause of death and is the most common cause of cancer in elderly men. Regarding to the low accuracy of screening methods such as prostate-specific antigen (PSA), Digital Rectal Examination (DRE) and trans rectal ultrasound (TRUS) in detection and localization of tumor, Magnetic Resonance Imaging (MRI) and Diffusion Weighted Imaging (DWI) attracte...

متن کامل

Early detection of intravascular large B-cell lymphoma by 18FDG-PET/CT with diffuse FDG uptake in the lung without respiratory symptoms or chest CT abnormalities

Intravascular large B-cell lymphoma (IVLBCL) is a rare and aggressive subtype of systemic extranodal non-Hodgkin diffuse large B-cell lymphoma (DLBCL). We report a rare case of IVLBCL who showed diffuse 18F-fluorodeoxyglucose (FDG) uptake in the lung in FDG-positron emission tomography/computed tomography (PET/CT) without respiratory symptoms or chest CT abnormalities. Serum biochemical studies...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009